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Stubbs, C. and Haigh, J.M. and Kanfer, I. (1985) Determination of erythromycin in serum and urine by high performance liquid chromatography with ultraviolet detection. Journal of Pharmaceutical Sciences, 74 (10). pp. 1126-1128. ISSN 0022-3549
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Pub38.pdf 2234Kb |
Official URL: http://dx.doi.org/10.1002/jps.2600741027
Abstract
A high-performance liquid chromatographic analysis of erythromycin in human serum and urine with UV detection at 200 nm is presented. The method involves a solid-phase extraction procedure followed by a simple phase separation step and chromatography on a reversed-phase column. The method has sensitivity limits of 0.25 and 1.0 g/mL in serum and urine, respectively, and is sufficiently sensitive to monitor concentrations of erythromycin in human serum and urine after the administration of a single 500-mg erythromycin stearate tablet.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | erythromycin; drug determination; drug monitoring; drug urine level; erythrocin |
| Subjects: | Y Unknown > Subjects to be assigned |
| Divisions: | Faculty > Faculty of Pharmacy |
| ID Code: | 607 |
| Deposited By: | Prof John Haigh |
| Deposited On: | 05 Jun 2007 |
| Last Modified: | 06 Jan 2012 16:18 |
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