Potency ranking of two new topical corticosteroid creams containing 0.1% desonide or 0.05% halometasone utilizing the human skin-blanching assay

Meyer, E. and Smith, E.W. and Haigh, J.M. and Kanfer, I. (1988) Potency ranking of two new topical corticosteroid creams containing 0.1% desonide or 0.05% halometasone utilizing the human skin-blanching assay. Arzneimittel Forschung, 38 (12). pp. 1840-1843. ISSN 0004-4172

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Abstract

The human blanching assay was used to assess the potency of two new proprietary corticosteroid creams. The blanching abilities of 0.1% desonide cream and 0.05% halometasone cream were evaluated relative to the blanching elicited by 0.05% clobetasol 17-propionate cream, 0.1% betamethasone 17-valerate cream and 0.05% clobetasone 17-butyrate cream. The results of the trial indicated that the 0.1% desonide cream falls into the potent group of topical corticosteroid preparations and the 0.05% halomethasone cream falls into the moderately potent group.

Item Type:Article
Uncontrolled Keywords:Desonide; comparison, halometasone; potency; creams; topical preparations; corticosteroid; human skin-blanching assay
Subjects:Y Unknown > Subjects to be assigned
Divisions:Faculty > Faculty of Pharmacy
ID Code:620
Deposited By: Prof John Haigh
Deposited On:01 Jun 2007
Last Modified:06 Jan 2012 16:18
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